From the West End, take the Piccadilly line; estimate around 50 minutes to Terminal 5

https://lorenzoqqcc036.almoheet-travel.com/getting-to-heathrow-from-reading-and-oxford-direct-lines-and-links-1

From the West End, take the Piccadilly line; estimate around 50 minutes to Terminal 5, and consider traveling off-peak for a more comfortable journey.